Southern Meatloaf Recipe - The Seasoned Mom (2024)

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Classic comfort food with a Southern twist! You just can’t beat a moist, flavorful, tender Southern meatloaf recipe that brings your family together around the table. Pair the easy dinner with mashed potatoes, cornbread, collard greens, or green beans for a simple, cozy dish that everyone loves!

Southern Meatloaf Recipe - The Seasoned Mom (1)
Table of Contents
  1. How to Make Meatloaf | 1-Minute Video
  2. Southern Style Meatloaf Recipe
  3. Ingredients
  4. How to Make Southern Meatloaf
  5. What to Serve with Meatloaf
  6. Preparation and Storage Tips
  7. Traditional Meatloaf Recipe Variations
  8. Tips for the Best Southern Meatloaf Recipe
  9. Southern Meatloaf Recipe Recipe

How to Make Meatloaf | 1-Minute Video

Meatloaf has stood the test of time! It’s a classic family dinner that everyone at the table can agree on, made with affordable, hearty ingredients, and ready with minimal effort. My kids have come to love this meal just as much as I do, so it has become a regular in our kitchen.

Southern Style Meatloaf Recipe

So what makes this particular recipe so special? Inspired by a dish in Sarah Foster’s book, Southern Kitchen, this meatloaf includes a couple of Southern “twists.” Instead of oatmeal or breadcrumbs, cornbread crumbs serve as the binder in this Southern meatloaf recipe.

Additionally, instead of using just ground beef or even a “meatloaf mix,” this recipe uses a 50-50 blend of ground beef and ground pork. Pork is a source of Southern pride — especially for those of us born and raised in Virginia — so any chance that we get to add it to a meal, you know we will! I just love how much flavor these two simple ingredients — cornbread and pork — add to the traditional dish.

Southern Meatloaf Recipe - The Seasoned Mom (2)

Ingredients

One of the great things about classic meatloaf is that it only requires a handful of basic kitchen staples. This is a quick overview of the ingredients that you’ll need for a Southern meatloaf recipe. As always, specific measurements and complete cooking instructions are included in the printable recipe box at the bottom of the post.

  • Ketchup and Worcestershire sauce: together these two ingredients create a sweet and savory glaze that adds flavor and moisture to the inside and outside of the meatloaf.
  • Ground beef and ground pork: a flavorful combination that forms the base of the meatloaf. You can substitute with all ground beef, some ground turkey, or a “meatloaf mix,” which is typically a blend of ground beef, ground pork, and ground veal. Just make sure that you use 2 pounds of meat total.
  • Cornbread crumbs: a flavorful binder that keeps the meatloaf moist. You can use other fresh bread crumbs or cracker crumbs (like saltines) if you prefer.
  • Onion: adds moisture and savory flavor.
  • Eggs: give the meatloaf structure.
  • Basil, oregano, and garlic: for extra flavor.
  • Dijon mustard: adds moisture and a bit of zesty, acidic “bite.”
  • Salt and black pepper: to enhance the other flavors in the dish.
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Add Cornbread Crumbs for the Best Meatloaf Recipe

A somewhat unusual meatloaf ingredient, the cornbread crumbs replace regular breadcrumbs in this recipe. They add so much great flavor to the meal, and these fillers help to keep the texture of the meatloaf light. The crumbs absorb (and therefore retain) more moisture in the meatloaf so that it doesn’t become dry.

Since we eat cornbread or corn muffins almost weekly, this is a nice way to take advantage of any stale leftovers. Try my favorite skillet cornbread, honey cornbread, jalapeno cheddar cornbread, corn muffins, or old-fashioned corn sticks. In a pinch, you can use a store-bought mix, or purchase cornbread in the bakery at your grocery store.

Don’t have any cornbread to use in this recipe? Substitute with an equal amount of fresh bread crumbs, or use cracker crumbs!

Southern Meatloaf Recipe - The Seasoned Mom (4)

How to Make Southern Meatloaf

This Southern meatloaf recipe comes together quickly and easily, and then the oven does the work! I’ve included the detailed directions in the recipe card below, but here’s the quick version:

  1. Stir together ketchup and Worcestershire sauce in a small bowl. Set aside.
  2. Combine beef, pork, cornbread crumbs, onion, eggs, basil, Dijon, garlic, salt, oregano, pepper, and ½ cup of the ketchup mixture in a large bowl.
  3. Shape the mixture into a large rectangular loaf on a parchment-lined rimmed baking sheet.
  4. Spoon or brush the remaining ketchup mixture on top.
  5. Bake in a 375°F oven for about 1 hour, or until the meatloaf reaches an internal temperature of 160°F.
  6. Let the meatloaf rest for at least 5-10 minutes before slicing and serving.
Southern Meatloaf Recipe - The Seasoned Mom (5)

What to Serve with Meatloaf

This classic meatloaf recipe deserves equally delicious, cozy companions! Here are a few sides that go well with meatloaf for the ultimate comfort food dinner:

  • Party Potatoes, Mashed Potatoes with Sour Cream and Chives, Mashed Sweet Potatoes, Baked Potato Wedges, 3-Ingredient Buttermilk Mashed Potatoes, Easy Potato Salad, or Skin-On Mashed Red Potatoes
  • Duke’s Homemade Mac and Cheese,Creamy Baked Mac and Cheese,Crock Pot Mac and Cheese,Stovetop Shells and Cheese, orNo-Boil Easy Mac and Cheese
  • Jiffy Corn Casserole
  • ColeslaworVinegar Coleslaw
  • Arkansas Green Beans with BaconorSouthern-Style Green Beans
  • Broccoli Cauliflower Salad
  • Fried ApplesorBaked Apple Slices
  • Southern Succotash
  • Southern Collard GreensorSweet and Spicy Collard Greens with Bacon
  • Fried Okra
  • Broccoli and Cheese, Easy Broccoli Casserole, or Broccoli and Rice Casserole
  • Creamed Peas
  • Apple and Butternut Squash Casserole or Southern Squash Casserole
  • Cornbread Stuffing or Sausage Stuffing
  • Cast Iron Cornbread,Fluffy Bakery-Style Corn Muffins,Broccoli Cornbread,Southern Cornbread,Jiffy Cornbread with Creamed Corn,Sweet Cornbread,Pumpkin Cornbread,Cake Mix Cornbread,Skillet Cornbread,Corn Sticks,orHoney Cornbread
  • 3-Ingredient Sour Cream Muffins
  • Pumpkin BreadorPumpkin Muffins
  • Flaky Buttermilk Biscuits,3-Ingredient Buttermilk Biscuits,4-Ingredient Butter Swim Biscuits,7UP Biscuits,Sweet Potato Biscuits,Cheese Biscuits,Pumpkin Spice Biscuits,Cheddar Biscuits with Chives and Bacon, orDrop Biscuits
  • Wedge Salad,Classic Caesar Salad,House Salad with Candied Pecans, Mixed Greens with Dijon Vinaigrette,or aGreen Salad with Red Wine Vinaigrette
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Preparation and Storage Tips

  • Prep Ahead!You can prepare the meatloaf up to 24 hours in advance. Keep it covered in the refrigerator overnight. When ready to bake, allow the meatloaf to come to room temperature on the counter for at least 30 minutes while you preheat the oven.
  • How to Freeze Meatloaf:You canfreeze the meatloaf before or after cooking. Wrap cooked meatloaf tightly in aluminum foil and plastic wrap (or a freezer bag) and store in thefreezer for up to 3 months. Wrapped properly, the cooked meatloaf will stay freshin the refrigerator for at least 2-3 days. The leftovers are great on a meatloaf sandwich!
  • How to Reheat Meatloaf:Preheat the oven to 250°F. Place the meatloaf in an oven-safe baking dish and add 1 tablespoon of beef broth or water. Cover the dish with foil and bake for 25-30 minutes, or until meatloaf is warmed through.
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Traditional Meatloaf Recipe Variations

  • Instead of using a rimmed baking sheet, bake the meatloaf in a greased 9 x 5-inch loaf pan. At the end of baking, tilt the pan to drain off the grease.
  • Swap out the cornbread crumbs for other fresh breadcrumbs or cracker crumbs (such as saltine crackers).
  • Stir some brown sugar and/or apple cider vinegar into the ketchup mixture for a sweet and tangy twist.
  • Substitute yellow mustard for the Dijon mustard.
  • Try other herbs in addition to the basil and oregano. Good options include rosemary, chives, parsley, and thyme.
  • Instead of fresh cloves of garlic, use about ½ teaspoon of garlic powder.
  • Add more veggies to the meatloaf mixture, such as diced green bell peppers, grated zucchini, celery, or grated carrots. If you don’t want crisp vegetables in your finished meatloaf, you can sauté them in a skillet with butter before adding them to the beef and pork mixture.
  • Rather than a 50-50 combination of ground beef and ground pork, use just ground beef, some ground turkey, or a “meatloaf mix” of ground beef, ground pork, and ground veal.
  • Like meatloaf with cheese?Add a handful of grated cheddar (or other good melting cheese) to the meatloaf mixture!
Southern Meatloaf Recipe - The Seasoned Mom (8)

Southern Meatloaf Recipe - The Seasoned Mom (9)

Tips for the Best Southern Meatloaf Recipe

  • Use your handsor a fork to gently combine the meatloaf mixture.Be careful not to over-mix the meat, or it will become dense and mushy.
  • Lean ground beef (85%-93% lean) works best in this recipe. You need some fat to keep the meatloaf moist, but you don’t want it to be too greasy.
  • You donotneed to cover the meatloaf while it’s baking.
  • You’ll know the meatloaf is done when it reaches aninternal temperature of 160°Fon an instant read meat thermometer and the juices run clear.
  • Place a pan of warm water on the rack below the meatloaf in the oven. It’s not necessary, but this moist environment will prevent the meatloaf from cracking.
  • Garnish with fresh parsley or other herbs for a bright, colorful, and flavorful finishing touch.
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More Meatloaf Recipes to Try

Meatloaf Recipe with Oatmeal

1 hour hr 25 minutes mins

Mini Bacon Wrapped Meatloaf

1 hour hr 5 minutes mins

Turkey Meatloaf

1 hour hr 30 minutes mins

Southern Meatloaf Recipe - The Seasoned Mom (14)

Southern Meatloaf Recipe

5 from 4 votes

Prep: 20 minutes minutes

Cook: 1 hour hour

Resting Time 10 minutes minutes

Total: 1 hour hour 30 minutes minutes

Servings 6 people

Calories 446 kcal

Classic comfort food with a Southern twist! You just can't beat a moist, flavorful, tender Southern meatloaf recipe that brings your family together around the table.

Rate RecipePrint Recipe

Ingredients

  • ¾ cup ketchup
  • 2 tablespoons Worcestershire sauce
  • 1 lb. lean ground beef
  • 1 lb. ground pork
  • 1 cup day old cornbread crumbs or other fresh breadcrumbs
  • 1 small onion, grated or finely diced
  • 2 large eggs, lightly beaten
  • 1 tablespoon dried basil (or about ¼ cup chopped fresh basil)
  • 1 tablespoon Dijon mustard
  • 2 cloves garlic, pressed, grated, or minced
  • 2 teaspoons salt
  • 1 teaspoon dried oregano
  • ½ teaspoon ground black pepper
  • Optional, for serving: mashed potatoes, chopped fresh herbs for garnish

Instructions

  • Preheat oven to 375°F. Line a rimmed baking sheet with parchment paper; set aside.

  • In a small bowl, stir together ketchup and Worcestershire sauce. Set aside.

    Southern Meatloaf Recipe - The Seasoned Mom (15)

  • In a large bowl, use your hands or a fork to gently combine beef, pork, cornbread, onion, eggs, basil, Dijon, garlic, salt, oregano, pepper, and ½ cup of the ketchup mixture. Be careful not to mash or over-mix or the meatloaf will be dense or mushy.

    Southern Meatloaf Recipe - The Seasoned Mom (16)

  • On the prepared baking sheet, shape the meat mixture into a rectangular loaf.

  • Spread the remaining ketchup mixture on top.

    Southern Meatloaf Recipe - The Seasoned Mom (17)

  • Bake the meatloaf for about 1 hour, until the internal temperature is 160°F and the meatloaf is cooked through. (A pan of hot water in the oven, under the meatloaf, will prevent the top from cracking.) Remove from the oven and let rest for 5-10 minutes before slicing. Serve warm.

    Southern Meatloaf Recipe - The Seasoned Mom (18)

Video

Notes

  • Use your handsor a fork to gently combine the meatloaf mixture.Be careful not to over-mix the meat, or it will become dense and mushy.
  • Lean ground beef (85%-93% lean) works best in this recipe. You need some fat to keep the meatloaf moist, but you don’t want it to be too greasy.
  • You donotneed to cover the meatloaf while it’s baking.
  • You’ll know the meatloaf is done when it reaches aninternal temperature of 160°Fand the juices run clear.
  • Place a pan of warm water on the rack below the meatloaf in the oven. It’s not necessary, but this moist environment will prevent the meatloaf from cracking.
  • Instead of using a rimmed baking sheet, bake the meatloaf in a greased 9 x 5-inch loaf pan. At the end of baking, tilt the pan to drain off the grease.
  • Swap out the cornbread crumbs for other fresh breadcrumbs or cracker crumbs (such as saltine crackers).
  • Substitute yellow mustard for the Dijon mustard.
  • Try other herbs in addition to the basil and oregano. Good options include rosemary, chives, parsley, and thyme.
  • Add more vegetables to the meatloaf mixture, such as diced bell pepper or celery. If you don’t want crisp vegetables in your finished meatloaf, you can sauté them in a skillet with butter before adding them to the beef and pork mixture.
  • Rather than a 50-50 combination of ground beef and ground pork, use just ground beef, some ground turkey, or a “meatloaf mix” of ground beef, ground pork, and ground veal.
  • Like meatloaf with cheese?Add a handful of grated cheddar (or other good melting cheese) to the meatloaf mixture!
  • Recipe slightly adapted from Sarah Foster’s book, Southern Kitchen.

Nutrition

Serving: 1sliceCalories: 446kcalCarbohydrates: 25gProtein: 34gFat: 22gSaturated Fat: 8gPolyunsaturated Fat: 2gMonounsaturated Fat: 10gTrans Fat: 1gCholesterol: 156mgSodium: 1378mgPotassium: 732mgFiber: 2gSugar: 9gVitamin A: 257IUVitamin C: 4mgCalcium: 98mgIron: 5mg

Keyword: best meatloaf recipe, easy meatloaf recipe, southern meatloaf recipe

Course: Dinner

Cuisine: American, Southern

Author: Blair Lonergan

Don’t Forget to Share a Pic of What You Made!

Tag me on Instagram at @theseasonedmom

Southern Meatloaf Recipe - The Seasoned Mom (2024)

FAQs

What is the secret to a great meat loaf? ›

Try adding minced garlic, parsley, and thyme for a deeply savory taste. For mouthwateringly bold meatloaf, add Worcestershire sauce, Dijon mustard, and ketchup to the pre-baked mixture. This blend ensures that each bite is deliciously balanced with just a hint of sweetness.

Why milk instead of water in meatloaf? ›

Milk and other dairy products, like heavy cream and buttermilk, contain both water and fat, adding two types of moisture to our meatloaf. There's a long-held theory that milk can tenderize ground meat, and this is the reason often cited for cooking ground meat in milk to make a Bolognese-style ragù.

What happens if you put too many eggs in meatloaf? ›

Eggs bind the mixture, add flavor and increase browning, but too much egg will make a meat loaf tough and rubbery. Use about one egg per pound of meat. If using pork sausage, skip the egg. Milk adds flavor and moisture and helps distribute the seasoning throughout the mass.

What is the basic meatloaf formula? ›

The Basic Meatloaf Formula

All recipes for meatloaf start with the same basic formula: 2 pounds of ground meat and a “panade” made of bread or crackers soaked in milk. Along with a few eggs, this panade helps to hold the ground meat together and adds some essential moisture to the mix.

What ingredient keeps meatloaf from falling apart? ›

To help your meatloaf stay together add things such as eggs, bread, crushed croutons, oatmeal, crackers, and breadcrumbs, these are all key ingredients that help meat stick together. I hope that this helps to answer your question. What are the secrets to a firm, sliceable meatloaf that slices and won't fall apart?

Should I cook my meatloaf covered or uncovered? ›

Should I cook my meatloaf covered or uncovered? The meatloaf can be cooked uncovered. However, if you are concerned about it burning, you can cover the meatloaf with foil for the first 45 minutes and uncover it for the final 15 minutes to allow the meatloaf to brown on top.

How to make a Bobby Flay meatloaf? ›

directions
  1. Preheat oven to 425°F.
  2. Heat the oil in a large sauté pan over high heat. ...
  3. Whisk together the eggs and herbs in a large bowl. ...
  4. Whisk together the remaining ketchup and balsamic vinegar in a small bowl then brush the mixture over the entire loaf.
  5. Bake the meatloaf for approximately 1 to 1 1/4 hours.

Do you drain the juice from meatloaf? ›

When the meatloaf is done, remove the loaf pan from the oven and let the meatloaf rest for 10-15 minutes. Drain the extra fat and liquid off of the meatloaf and discard. Slice the meatloaf and serve.

Why is my meatloaf pink inside? ›

If the meatloaf is over 160°F, or 165°F if you used chicken or turkey, it's fully cooked and safe to consume even if it's still pink inside. The reason your meatloaf may still be pink in the middle when fully cooked is nitrates.

Can you overmix meatloaf? ›

Properly mixing a meatloaf prior to forming not only assures an evenness of flavor, but it also facilitates the linking of myosin in the meat, creating more of the protein network that will help to hold the slices together. However, overmixing can cause meatloaf to become springy, rubbery, and too dense.

What to do with all the grease in meatloaf? ›

A neat trick to soak up the grease under your meatloaf is to line the bottom of the pan with bread slices. The bread soaks up the grease as the loaf bakes. When the meatloaf is done, you can either throw out the bread or bake it to make some truly indulgent toast.

Is it better to cook meatloaf at 350 or 375? ›

The oven temperature is typically set at 350 degrees F for making meatloaf. That's the temperature you want to be sure to use so the meatloaf cooks and doesn't dry out. Too high, and the outer crust will burn before the interior is cooked all the way, too low and you don't get that delicious crust.

What can I use instead of breadcrumbs in meatloaf? ›

What Can You Substitute Bread Crumbs in Meatloaf With?
  1. Rolled Oats: When it comes to breadcrumb substitutes, rolled oats are one of the leading contenders. ...
  2. Crushed Crackers: An equally viable alternative is crushed crackers.
Sep 1, 2023

What is traditional meatloaf made of? ›

No bells and whistles - just a few ingredients including beef, egg, bread crumbs and a simple tomato-based topping. Use a gentle touch with ground beef. Over-mixing will result in burgers, meatballs or meatloaves with a firm texture.

Is meatloaf better on a sheet pan or loaf pan? ›

Not only does sheet pan meatloaf bake up faster than its traditional loaf-shaped cousin, it also has more surface area, meaning every bite is laden with that deliciously caramelized topping.

What can you put under meatloaf to soak up grease? ›

A neat trick to soak up the grease under your meatloaf is to line the bottom of the pan with bread slices. The bread soaks up the grease as the loaf bakes. When the meatloaf is done, you can either throw out the bread or bake it to make some truly indulgent toast.

Why does my meatloaf taste bland? ›

You're Not Sufficiently Seasoning the Meat

Before you cook the meatloaf, it's not a bad idea to very quickly saute a small nub of the meat mixture and give it a taste. If you feel like it needs a bit more seasoning, then adjust as necessary before baking the entire loaf. Black pepper is up to your discretion.

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